We use cookies on this site to enhance your experience.
By selecting “Accept” and continuing to use this website, you consent to the use of cookies.
My graduate training was completed at the University of Western Ontario. I received an MSc in Kinesiology (Neurovascular physiology) 2007 and a PhD in Medical Biophysics (The Impact of the Sympathetic NPY System on the Progression of breast cancer) in 2013. Prior to joining Laurier, I was a postdoctoral fellow at the Princess Margaret Cancer Center (Molecular Imaging) from 2013 to 2016 and at the University of Guelph (Department of Molecular and Cellular Biology) from 2016 to 2019.
My research interests focus on sympathetic neural regulation of the circulatory system at rest, during exercise and in diseased conditions. This research extends from molecular to systemic neurotransmitters/peptides induced responses.
Outside of the laboratory, my current pedagogical research interests include evaluating the utility of:
- digital learning platforms
- non-traditional assessment strategies
- problem based learning within the life sciences
- Wilfrid Laurier University Faculty of Science Early Career Teaching Excellence Award (2023)
- Dr. Alfred Jay Medical Biophysics Award (UWO, 2013)
- Bornath DP, McKie GL, McCarthy SF, Vanderheyden LW, Howe GJ, Medeiros PJ, Hazell TJ. Interleukin-6 is not involved in appetite regulation following moderate-intensity exercise in males with normal weight and obesity. Obesity (Silver Spring) 2023.
- McCarthy SF, Bornath DP, Jarosz C, Tucker JL, Medeiros PJ, Kenno KA, Hazell TJ. Intense interval exercise induces lactate accumulation and a greater suppression of acylated ghrelin compared with submaximal exercise in middle-aged adults. J Appl Physiol 2023
- Moniz SC, McCarthy SF, Broad AA, Medeiros PJ, Hazell TJ. The exercise-induced suppression of acylated ghrelin is blunted in the luteal phase of the menstrual cycle compared to the follicular phase following vigorous-intensity exercise. Appetite 2023
- Medeiros PJ, Pascetta SA, Kirsh SM, Al-Khazraji BK, Uniacke J. Expression of hypoxia inducible factor-dependent neuropeptide Y receptors Y1 and Y5 sensitizes hypoxic cells to NPY stimulation. J Biol Chem. 2022
- Ottolino-Perry K, Shahid A, DeLuca S, Son V, Sukhram M, Meng F, Liu ZA, Rapic S, Anantha NT, Wang SC, Chamma E, Gibson C, Medeiros PJ, Majeed S, Chu A, Wignall O, Pizzolato A, Rosen CF, Teene LL, Starr-Dunham D, Kulbatski I, Panzarella T, Done SJ, Easson AM, Leong WL, DaCosta RS. Intraoperative fluoresence imaging with aminolevulinic acid detects grossly occult breast cancer: a phase II radmoised control trial. Breast Cancer Res. 2021
- Timpano S., Guild BD., Specker EJ., Melanson G., Medeiros PJ., Sproul SLJ, Uniacke J. Physioxic human cell culture improves viability, metabolism, and mitochondrial morphology while reducing DNA damage. FASEB. 2019
- Islam H., Townsend LK., McKie G., Medeiros PJ., Gurd BJ., Hazell TJ. Potential involvement of lactate and interleukin-6 in the appetite-regulatory hormonal response to an acute exercise bout. J App Physiol. 2017
- Olver TD., McDonald MW., Grisé KN., Allen MD., Medeiros PJ., Lacefield JC., Jackson DN., Rice CL., Melling CW., Noble EG., Shoemaker JK. Exercise Training Enhances Insulin-Stimulated Nerve Arterial Vasodilation in Rats with Insulin-Treated Experimental Diabetes. Am J Physiol Regul Integr Comp Physiol. 2014
- Medeiros PJ., Jackson DN. Neuropeptide Y Y5-receptor activation on breast cancer cells acts as a paracrine system that stimulates VEGF expression and secretion to promote angiogenesis. Peptides. 2013
- Novielli NM., Al-Khazraji BK., Medeiros PJ., Jackson DN. Augmented sympathetic nervous system modulation attenuates the duration of vasodilatory and blood flow responses in prediabetic young Zucker Diabetic Fatty rats. PLOS One. 2012
- Twynstra J., Medeiros PJ., Jackson DN., Lacefield JC., Shoemaker JK. Y1R Control of Sciatic Nerve Blood Flow in the Wistar Kyoto Rat. Microvasc Res. 2012
- Al-Khazraji BK., Novielli NM., Medeiros PJ., Goldman D., Jackson DN. A simple “streak method” for quantifying and characterizing red blood cell velocity profiles and blood flow in rat skeletal muscle arteriolar networks. Microcirculation. 2012
- Al-Khazraji BK., Medeiros PJ., Novielli NM., Jackson DN., An automated cell-counting algorithm for fluorescently-stained cells in migration assays. Biol Proced Online. 2011
- Medeiros PJ., Al-Khazraji BK., Novielli NM., Postovit LM., Chambers AF., Jackson DN., Neuropeptide Y stimulates proliferation and migration in the 4T1 breast cancer cell line. Int J Cancer. 2011
- Steinback CD., Salzer D., Medeiros PJ., Kowalchuk J., Shoemaker JK. Hypercapnic versus hypoxic control of cardiovascular, cardiovagal and sympathetic function. Am J Physiol Regul Integr Comp Physiol. 2009
- KP222/HN220: Human Physiology I
- HN320: Human Physiology II
- KP435/HE435: Exercise is Medicine
- KP422: Advanced Exercise Physiology
Contact Info:
T: 548.889-3851
Office location: BA521
Office hours: By appointment.
Languages spoken: English, Portuguese